5-(Difluoromethyl)-2-pyridinamine (>80%) - CAS 1211523-68-0

Catalog:	BB068489
Product Name:	5-(Difluoromethyl)-2-pyridinamine (>80%)
CAS:	1211523-68-0
Synonyms:	5-(DIFLUOROMETHYL)PYRIDIN-2-AMINE; 5-(Difluoromethyl)-2-pyridinamine; 5-Difluoromethyl-pyridin-2-ylamine; 2-Amino-5-(difluoromethyl)pyridine

Technical Data

IUPAC Name:	5-(difluoromethyl)pyridin-2-amine
Description:	5-(Difluoromethyl)-2-pyridinamine is used as a reactant in the preparation of uracil derivatives as Mer-Axl inhibitors.
Molecular Weight:	144.12
Molecular Formula:	C6H6N2F2
Canonical SMILES:	C1=CC(=NC=C1C(F)F)N
InChI:	InChI=1S/C6H6F2N2/c7-6(8)4-1-2-5(9)10-3-4/h1-3,6H,(H2,9,10)
InChI Key:	PFLFYOYMXCRVSS-UHFFFAOYSA-N
Melting Point:	> 60°C (dec.)
Solubility:	Chloroform (Sparingly, Heated, Sonicated), DMSO (Sparingly, Sonicated)
Appearance:	Orange to Dark Orange Solid
Storage:	-20°C Freezer, Under inert atmosphere
References:	Tarby, C., et al. PCT Int. Appl. (2019), WO 2019213340 A1 20191107..

Complexity:	108
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	144.04990452
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	144.04990452
Rotatable Bond Count:	1
Topological Polar Surface Area:	38.9Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.3