5-Chlorosaligenyl-N,N-diisopropylphosphoramidite - CAS 1620086-77-2
Catalog: |
BB069802 |
Product Name: |
5-Chlorosaligenyl-N,N-diisopropylphosphoramidite |
CAS: |
1620086-77-2 |
Synonyms: |
6-Chloro-N,N-bis(1-methylethyl)-4H-1,3,2-benzodioxaphosphorin-2-amine |
IUPAC Name: | 6-chloro-N,N-di(propan-2-yl)-4H-1,3,2-benzodioxaphosphinin-2-amine |
Description: | 5-Chlorosaligenyl-N,N-diisopropylphosphoramidite can be used in a method solid phase based synthesis of phosphatebridged nucleoside conjugates. |
Molecular Weight: | 287.72 |
Molecular Formula: | C13H19ClNO2P |
Canonical SMILES: | CC(C)N(C(C)C)P1OCC2=C(O1)C=CC(=C2)Cl |
InChI: | InChI=1S/C13H19ClNO2P/c1-9(2)15(10(3)4)18-16-8-11-7-12(14)5-6-13(11)17-18/h5-7,9-10H,8H2,1-4H3 |
InChI Key: | ZJPWJYRCWIYHMH-UHFFFAOYSA-N |
Solubility: | Acetonitrile (Slightly) |
Appearance: | Colourless Oil |
Storage: | Hygroscopic, -86°C Freezer, Under inert atmosphere |
References: | Sarac,I., et.al. U.S. Pat. Appl. Publ., (2015). |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 |
Signal Word: | Warning |
Complexity: | 270 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 287.0841935 |
Formal Charge: | 0 |
Heavy Atom Count: | 18 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 287.0841935 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 21.7Ų |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.9 |
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