5-Chloropyrazolo[1,5-a]pyrimidine - CAS 29274-24-6
Catalog: |
BB055575 |
Product Name: |
5-Chloropyrazolo[1,5-a]pyrimidine |
CAS: |
29274-24-6 |
Synonyms: |
5-chloropyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 5-chloro-; 5-Chloro-pyrazolo[1,5-a]pyrimidine |
IUPAC Name: | 5-chloropyrazolo[1,5-a]pyrimidine |
Description: | 5-Chloropyrazolo[1,5-a]pyrimidine was used in the preparation of β-substituted biarylphenylalanine amides as selective amino amide dipeptidyl peptidase IV inhibitors for treatment of type 2 diabetes. |
Molecular Weight: | 153.57 |
Molecular Formula: | C6H4ClN3 |
Canonical SMILES: | C1=CN2C(=CC=N2)N=C1Cl |
InChI: | InChI=1S/C6H4ClN3/c7-5-2-4-10-6(9-5)1-3-8-10/h1-4H |
InChI Key: | WEPRLWNMBTYGGD-UHFFFAOYSA-N |
References: | Edmondson, S.D., et al. J. Med. Chem., 49, 3614 (2006). |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-114163445-A | Raatinib intermediate and preparation method thereof | 20211206 |
CN-113336751-A | High-efficiency salt-induced kinase inhibitor and preparation method thereof | 20210531 |
CN-112010860-A | Benzyloxypyrazolopyrimidine compounds, pharmaceutical compositions and uses thereof | 20200805 |
CN-113278022-A | Pyrazolopyrimidine compounds, pharmaceutical compositions and uses thereof | 20200707 |
WO-2021228248-A1 | Fused aza-heterocyclic amide compound and use thereof | 20200515 |
WO-2021222522-A1 | Cd73 inhibiting 2,4-dioxopyrimidine compounds | 20200501 |
CN-113563341-A | Substituted pyrazolo [1,5-a ] pyrimidine compounds as Trk inhibitors | 20200429 |
WO-2021197467-A1 | Multi-target anti-tumor compound, preparation method therefor and use thereof | 20200402 |
WO-2021058595-A1 | Herbicidal compounds | 20190924 |
TW-202126656-A | Herbicidal compounds | 20190924 |
Complexity: | 130 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 153.0093748 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 153.0093748 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 30.2Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.3 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS