5-(Chloromethyl)-2-methoxypyridine - CAS 101990-70-9
Catalog: |
BB000722 |
Product Name: |
5-(Chloromethyl)-2-methoxypyridine |
CAS: |
101990-70-9 |
Synonyms: |
5-(chloromethyl)-2-methoxypyridine; 5-(chloromethyl)-2-methoxypyridine |
IUPAC Name: | 5-(chloromethyl)-2-methoxypyridine |
Description: | 5-(Chloromethyl)-2-methoxypyridine (CAS# 101990-70-9) is used in preparation of pyrazolopyridine compounds as RET kinase inhibitor for treatment of RET-related diseases. |
Molecular Weight: | 157.60 |
Molecular Formula: | C7H8ClNO |
Canonical SMILES: | COC1=NC=C(C=C1)CCl |
InChI: | InChI=1S/C7H8ClNO/c1-10-7-3-2-6(4-8)5-9-7/h2-3,5H,4H2,1H3 |
InChI Key: | YNCJGPOTUFPVTB-UHFFFAOYSA-N |
Boiling Point: | 236.1 °C at 760 mmHg |
Density: | 1.173 g/cm3 |
Storage: | Inert atmosphere, Store in freezer, under -20 °C |
LogP: | 1.82900 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113045569-A | Compounds useful as RET kinase inhibitors and uses thereof | 20191227 |
WO-2021129841-A1 | Compound used as ret kinase inhibitor and application thereof | 20191227 |
US-2021236663-A1 | Compounds and probes for imaging huntingtin protein | 20191218 |
WO-2021127265-A1 | Compounds and probes for imaging huntingtin protein | 20191218 |
CN-112851664-A | Pyrazolo [1,5-a ] pyridine-3-nitrile compound and application thereof in medicine | 20191112 |
Complexity: | 99.6 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 157.0294416 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 157.0294416 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 22.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.5 |
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