5-Chloro-8-quinolinol - CAS 130-16-5
Catalog: |
BB007057 |
Product Name: |
5-Chloro-8-quinolinol |
CAS: |
130-16-5 |
Synonyms: |
5-chloroquinolin-8-ol |
Application: |
Cloxiquine could be commonly used as anti-infective and antioxidant agent. |
IUPAC Name: | 5-chloroquinolin-8-ol |
Description: | Cloxiquine, a quinoline derivative, could be commonly used as anti-infective and antioxidant agent. |
Molecular Weight: | 179.60 |
Molecular Formula: | C9H6ClNO |
Canonical SMILES: | C1=CC2=C(C=CC(=C2N=C1)O)Cl |
InChI: | InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H |
InChI Key: | CTQMJYWDVABFRZ-UHFFFAOYSA-N |
Melting Point: | 121-126 °C |
Purity: | 95 % |
Density: | 1.412 g/cm3 |
Solubility: | DMSO : 34mg/mL |
Appearance: | Light beige solid |
Storage: | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
MDL: | MFCD00006788 |
LogP: | 2.59380 |
GHS Hazard Statement: | H315 (99.61%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113429963-A | Continuous color-changing fluorescent anti-counterfeiting material and preparation method and application thereof | 20210624 |
CN-113461610-A | Preparation process and preparation system of cloquintocet-mexyl | 20210510 |
CN-113248547-A | Nitrosyl ruthenium complex, nitrosyl ruthenium complex and serum protein complex, and preparation method and application thereof | 20210427 |
CN-113135851-A | Synthesis method of cloquintocet-mexyl | 20210426 |
CN-113121431-A | Method for chemically synthesizing cloquintocet-mexyl | 20210418 |
PMID | Publication Date | Title | Journal |
23571415 | 20130601 | Structure-based identification of OATP1B1/3 inhibitors | Molecular pharmacology |
23445471 | 20130328 | Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction | Journal of medicinal chemistry |
22695927 | 20120901 | Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode | Journal of fluorescence |
22167242 | 20120301 | Novel anti-Cryptosporidium activity of known drugs identified by high-throughput screening against parasite fatty acyl-CoA binding protein (ACBP) | The Journal of antimicrobial chemotherapy |
22160146 | 20120201 | Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation | The Journal of antimicrobial chemotherapy |
Complexity: | 165 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 179.0137915 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 179.0137915 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 33.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.9 |
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Quinoline/Isoquinoline
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