5-Chloro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide - CAS 75993-42-9

Catalog:	BB068812
Product Name:	5-Chloro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS:	75993-42-9
Synonyms:	5-Chloro-2,6-dihydroxypyridine-3-carboxamide

Technical Data

IUPAC Name:	5-chloro-2-hydroxy-6-oxo-1H-pyridine-3-carboxamide
Description:	5-Chloro-6-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.
Molecular Weight:	188.57
Molecular Formula:	C6H5ClN2O3
Canonical SMILES:	C1=C(C(=O)NC(=C1C(=O)N)O)Cl
InChI:	InChI=1S/C6H5ClN2O3/c7-3-1-2(4(8)10)5(11)9-6(3)12/h1H,(H2,8,10)(H2,9,11,12)
InChI Key:	AMYFOJLIWDFAFA-UHFFFAOYSA-N
References:	Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014).

Complexity:	319
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	187.9988697
Formal Charge:	0
Heavy Atom Count:	12
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	187.9988697
Rotatable Bond Count:	1
Topological Polar Surface Area:	92.4Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0