5-Chloro-3-iodo-pyridin-2-ylamine - CAS 211308-81-5
Catalog: |
BB016629 |
Product Name: |
5-Chloro-3-iodo-pyridin-2-ylamine |
CAS: |
211308-81-5 |
Synonyms: |
5-chloro-3-iodopyridin-2-amine |
IUPAC Name: | 5-chloro-3-iodopyridin-2-amine |
Description: | 5-Chloro-3-iodo-pyridin-2-ylamine (CAS# 211308-81-5) is a useful synthetic intermediate. It was used in the rational design of highly selective spleen tyrosine kinase inhibitors. It was also used to synthesize azaindole derivatives with antibacterial and antifungal activities. |
Molecular Weight: | 254.46 |
Molecular Formula: | C5H4ClIN2 |
Canonical SMILES: | C1=C(C=NC(=C1I)N)Cl |
InChI: | InChI=1S/C5H4ClIN2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9) |
InChI Key: | DIONPYCYVWCDIG-UHFFFAOYSA-N |
Boiling Point: | 306.9 °C at 760 mmHg |
Melting Point: | 137-138 °C |
Purity: | 95 % |
Density: | 2.139 g/cm3 |
Appearance: | Yellow dust |
MDL: | MFCD07644578 |
LogP: | 2.50300 |
GHS Hazard Statement: | H302 (80%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113214254-A | Hole-transport-type main body material, preparation method thereof and application thereof in preparation of organic electroluminescent device | 20210409 |
WO-2021057975-A1 | Mutant idh2 inhibitor and application thereof | 20190929 |
CN-112552331-A | Heterocyclic compound and organic light-emitting device including the same | 20190926 |
KR-20210037061-A | Heterocyclic compound and organic light emitting device including the same | 20190926 |
US-2021098720-A1 | Heterocyclic compound and organic light-emitting device including the same | 20190926 |
Complexity: | 101 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 253.91077 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 253.91077 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 38.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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Related Functional Groups
Amines and Anilines
Pyridines
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