(5-Chloro-2-thienyl)(3-hydroxy-1-azetidinyl)methanone - CAS 1341527-09-0
Catalog: |
BB069735 |
Product Name: |
(5-Chloro-2-thienyl)(3-hydroxy-1-azetidinyl)methanone |
CAS: |
1341527-09-0 |
Synonyms: |
(5-Chloro-2-thienyl)(3-hydroxy-1-azetidinyl)methanone; (5-chlorothiophen-2-yl)-(3-hydroxyazetidin-1-yl)methanone; (5-Chlorothiophen-2-yl)(3-hydroxyazetidin-1-yl)methanone |
IUPAC Name: | (5-chlorothiophen-2-yl)-(3-hydroxyazetidin-1-yl)methanone |
Description: | (5-Chloro-2-thienyl)(3-hydroxy-1-azetidinyl)methanone is used in an impurity in the synthesis of Rivaroxaban, a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor. |
Molecular Weight: | 217.67 |
Molecular Formula: | C8H8ClNO2S |
Canonical SMILES: | C1C(CN1C(=O)C2=CC=C(S2)Cl)O |
InChI: | InChI=1S/C8H8ClNO2S/c9-7-2-1-6(13-7)8(12)10-3-5(11)4-10/h1-2,5,11H,3-4H2 |
InChI Key: | FCVRTRIBVGXFTB-UHFFFAOYSA-N |
References: | Ansell, J., et al. Drugs, 64, 1 (2004), Eriksson, B., et al. J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al. Clin. Pharmacol. Ther., 78, 412 (2005),. |
Complexity: | 220 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 216.9964274 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 216.9964274 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 68.8Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.5 |
-
Catalog: BB014781
1,4-Benzodioxane-6-carbonitrile
Detail
-
Catalog: BB006975
(3R)-N-methyloxolan-3-amine hydrochloride
Detail
-
Catalog: BB016397
1-methyl-3-(1,3-thiazol-2-yl)-1H-pyrazole-5-carbaldehyde
Detail
-
Catalog: BB077194
(S)-(-)-1,2-epoxydecane
Detail
-
Catalog: BB016398
4-chloro-6-methylimidazo[2,1-f][1,2,4]triazine
Detail
-
Catalog: BB016437
2-amino-3-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}propanenitrile
Detail
-
Catalog: BB012200
8-(tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-chromen-4-one
Detail
-
Catalog: BB054600
3-glycidoxypropyltrimethoxysilane
Detail
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS