5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide - CAS 16673-34-0
Catalog: |
BB012307 |
Product Name: |
5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide |
CAS: |
16673-34-0 |
Synonyms: |
5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide |
IUPAC Name: | 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide |
Description: | Glibenclamide Impurity A is an impurity arising in the synthesis of Glyburide. |
Molecular Weight: | 368.84 |
Molecular Formula: | C16H17ClN2O4S |
Canonical SMILES: | COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N |
InChI: | InChI=1S/C16H17ClN2O4S/c1-23-15-7-4-12(17)10-14(15)16(20)19-9-8-11-2-5-13(6-3-11)24(18,21)22/h2-7,10H,8-9H2,1H3,(H,19,20)(H2,18,21,22) |
InChI Key: | KVWWTCSJLGHLRM-UHFFFAOYSA-N |
Melting Point: | 214-215 °C |
Purity: | > 95 % |
Density: | 1.356 g/cm3 |
Appearance: | Off-white to light yellow solid |
MDL: | MFCD00193756 |
LogP: | 4.14050 |
GHS Hazard Statement: | H302 (66.67%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021198511-A1 | Methods and compositions for treatment of sars-cov-2 infection | 20200403 |
WO-2021188984-A1 | Prevention and intervention of infarct expansion following hemorrhagic infarctions | 20200320 |
WO-2021185912-A1 | Method for the treatment nlrp3-associated diseases | 20200319 |
WO-2021087344-A1 | Theranostics for hypertension induced myocardial microbleeds | 20191031 |
US-2020368257-A1 | Compositions and Methods for the Treatment of Inflammation in Urological Pathology | 20190520 |
PMID | Publication Date | Title | Journal |
26422006 | 20160310 | Inhibiting the Inflammasome: A Chemical Perspective | Journal of medicinal chemistry |
18023561 | 20080315 | Adhesion of Pseudomonas putida NCIB 9816-4 to a naphthalene-contaminated soil | Colloids and surfaces. B, Biointerfaces |
15664331 | 20050225 | Liquid chromatography-electrospray tandem mass spectrometry method for determination of indapamide in serum for single/multiple dose bioequivalence studies of sustained release formulations | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
11999993 | 20020301 | Biodegradation of toluene by a lab-scale biofilter inoculated with Pseudomonas putida DK-1 | Environmental technology |
Complexity: | 515 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 368.0597559 |
Formal Charge: | 0 |
Heavy Atom Count: | 24 |
Hydrogen Bond Acceptor Count: | 5 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 368.0597559 |
Rotatable Bond Count: | 6 |
Topological Polar Surface Area: | 107 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.4 |
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