5-Carboxyfluorescein - CAS 76823-03-5
Catalog: |
BB035709 |
Product Name: |
5-Carboxyfluorescein |
CAS: |
76823-03-5 |
Synonyms: |
4-carboxyfluorescein; 5-FAM; 3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxylic acid |
IUPAC Name: | 3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid |
Description: | 5-Carboxyfluorescein is a derivative of fluorescein that can be used to label biomolecules through interacting with primary amines. |
Molecular Weight: | 376.32 |
Molecular Formula: | C21H12O7 |
Canonical SMILES: | C1=CC2=C(C=C1C(=O)O)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O |
InChI: | InChI=1S/C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21/h1-9,22-23H,(H,24,25) |
InChI Key: | NJYVEMPWNAYQQN-UHFFFAOYSA-N |
Boiling Point: | 725.2±60.0 °C (Predicted) |
Melting Point: | 368-372 °C |
Purity: | ≥ 95 % |
Density: | 1.73±0.1 g/cm3 (Predicted) |
Solubility: | Soluble in DMF; Slightly soluble in DMSO, Methanol |
Appearance: | Yellow solid |
Storage: | -20 °C |
MDL: | MFCD00036874 |
Emission: | 518 nm |
Excitation: | 492 nm |
LogP: | 3.36400 |
GHS Hazard Statement: | H315 (20%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
22965716 | 20120901 | Implementation of a genetically tuned neural platform in optimizing fluorescence from receptor-ligand binding interactions on microchips | Electrophoresis |
22387888 | 20120530 | Suppression of efflux transporters in the intestines of endotoxin-treated rats | International journal of pharmaceutics |
22545861 | 20120516 | In vitro selection of functional lantipeptides | Journal of the American Chemical Society |
22276994 | 20120420 | Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction | ACS chemical biology |
22272228 | 20120101 | A reliable method for the selection of exploitable melanoma archival paraffin embedded tissues for transcript biomarker profiling | PloS one |
Complexity: | 637 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 376.05830272 |
Formal Charge: | 0 |
Heavy Atom Count: | 28 |
Hydrogen Bond Acceptor Count: | 7 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 376.05830272 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 113 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.9 |
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