5-(Aminomethyl)-N,N-dimethylpyridin-2-amine - CAS 354824-17-2
Catalog: |
BB022655 |
Product Name: |
5-(Aminomethyl)-N,N-dimethylpyridin-2-amine |
CAS: |
354824-17-2 |
Synonyms: |
5-(aminomethyl)-N,N-dimethyl-2-pyridinamine; 5-(aminomethyl)-N,N-dimethylpyridin-2-amine |
IUPAC Name: | 5-(aminomethyl)-N,N-dimethylpyridin-2-amine |
Description: | 5-(Aminomethyl)-N,N-dimethylpyridin-2-amine (CAS# 354824-17-2) is a useful synthetic intermediate. It is used to prepare nicotinamide phosphoribosyltransferase (NAMPT) inhibitors for therapy of diseases such as cancer. |
Molecular Weight: | 151.21 |
Molecular Formula: | C8H13N3 |
Canonical SMILES: | CN(C)C1=NC=C(C=C1)CN |
InChI: | InChI=1S/C8H13N3/c1-11(2)8-4-3-7(5-9)6-10-8/h3-4,6H,5,9H2,1-2H3 |
InChI Key: | YJIDKQVYACIBPR-UHFFFAOYSA-N |
MDL: | MFCD08272104 |
LogP: | 1.30660 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P260, P261, P264, P270, P271, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021076617-A1 | Broad spectrum anti-cancer compounds | 20191014 |
WO-2020114947-A1 | Heteroaromatic compounds as vanin inhibitors | 20181203 |
US-2019389854-A1 | Therapeutic componds and methods of use thereof | 20180620 |
US-11014921-B2 | Therapeutic compounds and methods of use thereof | 20180620 |
AU-2016342310-A1 | Novel ferroportin inhibitors | 20151023 |
Complexity: | 114 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 151.110947427 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 151.110947427 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 42.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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Amines and Anilines
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