5-Amino-1-naphthol - CAS 83-55-6

Name: 5-Amino-1-naphthol
Brand: BOC Sciences
Rating: 5 (1 reviews)

Technical Data

IUPAC Name:	5-aminonaphthalen-1-ol
Description:	5-Amino-1-naphthol (CAS# 83-55-6) is a reagent in the preparation of 5-hydroxy duloxetine. It is also used in the preparation of tetrahydronaphthol-, naphthol-, sulfonamide-, phenyl-, and heterocyclic-TRPV1 antagonists.
Molecular Weight:	159.18
Molecular Formula:	C10H9NO
Canonical SMILES:	C1=CC2=C(C=CC=C2O)C(=C1)N
InChI:	InChI=1S/C10H9NO/c11-9-5-1-4-8-7(9)3-2-6-10(8)12/h1-6,12H,11H2
InChI Key:	ZBIBQNVRTVLOHQ-UHFFFAOYSA-N
Boiling Point:	378.3 °C at 760 mmHg
Melting Point:	189 °C
Purity:	95 %
Density:	1.281 g/cm³
Appearance:	Pale purple to brown-purple crystalline powder
Storage:	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
MDL:	MFCD00041826
LogP:	2.70880

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-113416141-A	Preparation method of 5-amino-1-naphthol hydrochloride	20210714
CN-113355050-A	Biological aldehyde-free glue, biological composite material and preparation method thereof	20210712
CN-112521296-B	Diamine compound, heat-resistant resin or heat-resistant resin precursor using same, photosensitive resin composition, cured film, and display device	20210205
CN-112939915-A	Diamine monomer for photosensitive resin, polyimide precursor, photosensitive resin composition, and use thereof	20210205
CN-112500570-A	Flexible display device, polyamic acid varnish for display, and polyimide film	20210204

PMID	Publication Date	Title	Journal
24599669	20140401	Kinetic and spectroscopic characterization of 1-naphthol 2-hydroxylase from Pseudomonas sp. strain C5	Applied biochemistry and biotechnology
20949369	20110601	1-naphthol 2-hydroxylase from Pseudomonas sp. strain C6: purification, characterization and chemical modification studies	Biodegradation
20199039	20100325	The interaction of 5-(alkoxy)naphthalen-1-amine with bovine serum albumin and its effect on the conformation of protein	The journal of physical chemistry. B
19893237	20091101	5-Amino-1-naphthol: two-dimensional sheets built up from R(4)(4)(18) rings formed by O-H...N, N-H...O and pi-pi interactions	Acta crystallographica. Section C, Crystal structure communications
21578535	20091031	5-Amino-1-naphthol	Acta crystallographica. Section E, Structure reports online

Complexity:	160
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	159.068413911
Formal Charge:	0
Heavy Atom Count:	12
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	159.068413911
Rotatable Bond Count:	0
Topological Polar Surface Area:	46.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.5