5,7-Dichloro-8-quinolinol - CAS 773-76-2
Catalog: |
BB035912 |
Product Name: |
5,7-Dichloro-8-quinolinol |
CAS: |
773-76-2 |
Synonyms: |
5,7-dichloroquinolin-8-ol |
Application: |
Anti-Bacterial Agents |
IUPAC Name: | 5,7-dichloroquinolin-8-ol |
Description: | Chloroxine has bacteriostatic, fungistatic and antiprotozoal properties. It is effective against Streptococci, Staphylococci, Candida, Candida albicans, Shigella and Trichomonads. |
Molecular Weight: | 214.05 |
Molecular Formula: | C9H5Cl2NO |
Canonical SMILES: | C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1 |
InChI: | InChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H |
InChI Key: | WDFKMLRRRCGAKS-UHFFFAOYSA-N |
Boiling Point: | 355 °C |
Melting Point: | 180-182 °C |
Purity: | > 98 % |
Density: | 1.538 g/cm3 |
Solubility: | 1.38e-01 g/L |
Appearance: | Light yellow solid |
MDL: | MFCD00006786 |
LogP: | 3.24720 |
GHS Hazard Statement: | H302 (89.58%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
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PMID | Publication Date | Title | Journal |
23571415 | 20130601 | Structure-based identification of OATP1B1/3 inhibitors | Molecular pharmacology |
23445471 | 20130328 | Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction | Journal of medicinal chemistry |
22695927 | 20120901 | Synthesis and characterization of 8-hydroxyquinoline complexes of tin(IV) and their application in organic light emitting diode | Journal of fluorescence |
21739938 | 20110811 | Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase | Journal of medicinal chemistry |
21516114 | 20110601 | Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy | Nature chemical biology |
Complexity: | 191 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 212.9748192 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 212.9748192 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 33.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.5 |
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