5,6,7,8-Tetrahydro-3-methyl-1,2,4-triazolo[4,3-a]pyrazine - CAS 886886-04-0
Catalog: |
BB057574 |
Product Name: |
5,6,7,8-Tetrahydro-3-methyl-1,2,4-triazolo[4,3-a]pyrazine |
CAS: |
886886-04-0 |
Synonyms: |
3-Methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 3-Methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-〈a]pyrazine |
IUPAC Name: | 3-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine |
Description: | 5,6,7,8-Tetrahydro-3-methyl-1,2,4-triazolo[4,3-a]pyrazine is used as a reagent to synthesize pyrrolo[2,3-b]pyridine compounds which have the potential to act as antiviral agents against specific viruses of the retrovirus family (such as the human immunodeficiency virus [HIV]). |
Molecular Weight: | 138.17 |
Molecular Formula: | C6H10N4 |
Canonical SMILES: | CC1=NN=C2N1CCNC2 |
InChI: | InChI=1S/C6H10N4/c1-5-8-9-6-4-7-2-3-10(5)6/h7H,2-4H2,1H3 |
InChI Key: | WRGHYZWPWNOJEF-UHFFFAOYSA-N |
References: | De la Rosa, M. Preparation of pyrrolo[2,3-b]pyridine compounds as antiviral agents and methods for treating HIV. PCT Int. Appl. WO 2014009794, 2014.. |
GHS Hazard Statement: | H301 (97.44%): Toxic if swallowed [Danger Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P301+P316, P321, P330, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021102468-A1 | Substituted 1,5-naphthyridines or quinolines as alk5 inhibitors | 20191122 |
WO-2019192506-A1 | Immunomodulators, compositions and methods thereof | 20180403 |
CN-107540677-B | Sitagliptin derivative or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 20170930 |
US-10047094-B1 | Process for the preparation of triazole and salt thereof | 20170210 |
US-2018230151-A1 | Process for the preparation of triazole and salt thereof | 20170210 |
AU-2018212438-A1 | Bicyclic bis-heteroaryl derivatives as modulators of protein aggregation | 20170126 |
BR-112019011924-A2 | Bicyclic bisheteroaryl derivatives as protein aggregation modulators | 20170126 |
CA-3045221-A1 | Bicyclic bis-heteroaryl derivatives as modulators of protein aggregation | 20170126 |
EP-3573986-A1 | Bicyclic bis-heteroaryl derivatives as modulators of protein aggregation | 20170126 |
IL-267993-D0 | History of bitumen-troisarial bites as modulators of protein accumulation | 20170126 |
Complexity: | 127 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 138.090546336 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 138.090546336 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 42.7Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1.1 |
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