5,6,7,8-Tetrahydro-1-naphthol - CAS 529-35-1

Name: 5,6,7,8-Tetrahydro-1-naphthol
Brand: BOC Sciences
Rating: 5 (1 reviews)

Technical Data

IUPAC Name:	5,6,7,8-tetrahydronaphthalen-1-ol
Description:	5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
Molecular Weight:	148.20
Molecular Formula:	C10H12O
Canonical SMILES:	C1CCC2=C(C1)C=CC=C2O
InChI:	InChI=1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h3,5,7,11H,1-2,4,6H2
InChI Key:	SCWNNOCLLOHZIG-UHFFFAOYSA-N
Boiling Point:	264-265 °C (705 torr)
Melting Point:	67-71 °C
Purity:	95 %
Density:	1.1 g/cm³
Appearance:	White powder to crystalline powder
Storage:	Room temperature.
MDL:	MFCD00001734
LogP:	2.27100

GHS Hazard Statement:	H302 (66.92%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Danger

Publication Number	Title	Priority Date
CN-112409254-A	Preparation method of naphthoquine phosphate	20201208
CN-112374968-A	Application of supported catalyst in selective hydrogenation reaction of naphthalene derivative	20201130
CN-112374969-A	Application of supported noble metal catalyst in selective hydrogenation reaction of naphthalene derivative	20201130
CN-112409145-A	Preparation method of 1-tetralone	20201113
CN-113149941-A	Ether compound and pharmaceutical application thereof in preventing and treating diabetes and metabolic syndrome	20200122

PMID	Publication Date	Title	Journal
20354970	20110301	Fluorescence quenching studies of nitrated polycyclic aromatic hydrocarbons	Luminescence : the journal of biological and chemical luminescence
18816459	20090201	High-performance liquid chromatography determination of nitrated polycyclic aromatic hydrocarbons by indirect fluorescence detection	Biomedical chromatography : BMC
12524123	20030201	Non-radiative depletion of the excited electronic states of 9-cyanoanthracene in presence of tetrahydronaphthols	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Complexity:	133
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	148.088815002
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	1
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	148.088815002
Rotatable Bond Count:	0
Topological Polar Surface Area:	20.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.9