IUPAC Name: | bis[5-(5,5-dimethyl-1,3-dioxan-2-yl)-2-methoxyphenyl]-(4-methoxyphenyl)methanol |
Description: | 5-(5,5-Dimethyl-1,3-dioxan-2-yl)-α-[5-(5,5-dimethyl-1,3-dioxan-2-yl)-2-methoxyphenyl]-2-methoxy-α-(4-methoxyphenyl)benzenemethanol is an intermediate in the synthesis of VP 14637 (V785000), an inhibitor used to treat respiratory syncytial virus infections. |
Molecular Weight: | 578.69 |
Molecular Formula: | C34H42O8 |
Canonical SMILES: | CC1(COC(OC1)C2=CC(=C(C=C2)OC)C(C3=CC=C(C=C3)OC)(C4=C(C=CC(=C4)C5OCC(CO5)(C)C)OC)O)C |
InChI: | InChI=1S/C34H42O8/c1-32(2)18-39-30(40-19-32)22-8-14-28(37-6)26(16-22)34(35,24-10-12-25(36-5)13-11-24)27-17-23(9-15-29(27)38-7)31-41-20-33(3,4)21-42-31/h8-17,30-31,35H,18-21H2,1-7H3 |
InChI Key: | HJLHQRLHVSSREH-UHFFFAOYSA-N |
Solubility: | Ethyl Acetate |
Appearance: | White Solid |
References: | Andries, K., et al. Antiviral Res., 60, 209 (2003), Douglas, J., et al. J. Virol., 77, 5054 (2003), Cianci, C., et al. Antimicrob. Agents Chemother., 48, 413 (2004),. |
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