5-(4-Chlorophenyl)furfural - CAS 34035-03-5

Name: 5-(4-Chlorophenyl)furfural
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB021939
Product Name:	5-(4-Chlorophenyl)furfural
CAS:	34035-03-5
Synonyms:	5-(4-chlorophenyl)furan-2-carbaldehyde

Technical Data

IUPAC Name:	5-(4-chlorophenyl)furan-2-carbaldehyde
Description:	5-(4-Chlorophenyl)furfural (CAS# 34035-03-5) is a metabolite of Azimilide (A926950, 2 HCl); an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of Azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide is also being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction.
Molecular Weight:	206.63
Molecular Formula:	C11H7ClO2
Canonical SMILES:	C1=CC(=CC=C1C2=CC=C(O2)C=O)Cl
InChI:	InChI=1S/C11H7ClO2/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-7H
InChI Key:	ROJGJNINTRCMBL-UHFFFAOYSA-N
Boiling Point:	350.7 °C at 760 mmHg
Melting Point:	128-131 °C
Purity:	95 %
Density:	1.282 g/cm³
Appearance:	Yellow to brown powder
MDL:	MFCD00195947
LogP:	3.41250

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
KR-102114389-B1	Novel sodium channel inhibitor compound, preparation method thereof, and pharmaceutical composition for prevention or treatment of sodium channel related diseases containing the same as an active ingredient	20180502
KR-20190126525-A	Novel sodium channel inhibitor compound, preparation method thereof, and pharmaceutical composition for prevention or treatment of sodium channel related diseases containing the same as an active ingredient	20180502
KR-101897797-B1	Cyclic amino substituted 5-arylfuran-2-carboxamide, preparation method thereof, and pharmaceutical composition for use in preventing or treating Urotensin-â…¡ receptor activity related diseases containing the same as an active ingredient	20170421
CN-108203450-B	Preparation method and application of amino phosphonate containing arylpyrazole compound	20161219
KR-101859074-B1	Novel glycine amide compound or pharmaceutically acceptable salts thereof, preparation method thereof and pharmaceutical composition for prevention or treatment of diseases induced by activation of sodium channel containing the same as an active ingredient	20160128

Complexity:	200
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	206.0134572
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	206.0134572
Rotatable Bond Count:	2
Topological Polar Surface Area:	30.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	3.1