Description: | 5-(1,1-Dimethylethyl) 1-Methyl N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate is an intermediate in the synthesis of Methotrexate α-Methyl Ester (M260700) which is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic. |
Molecular Weight: | 524.57 |
Molecular Formula: | C25H32N8O5 |
References: | Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al. N. Engl. J. Med., 312, 818 (1985),. |
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