L-Dihydroorotic acid - CAS 5988-19-2
Catalog: |
BB030547 |
Product Name: |
L-Dihydroorotic acid |
CAS: |
5988-19-2 |
Synonyms: |
(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid; (4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid |
IUPAC Name: | (4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid |
Description: | (4S)-2,6-Dioxo-1,3-diazinane-4-carboxylic Acid (CAS# 5988-19-2) is used as a reactant in the preparation of long acting Gonadotrophin-releasing hormone (GnRH) antagonist containing p-ureido-phenylalanine. |
Molecular Weight: | 158.11 |
Molecular Formula: | C5H6N2O4 |
Canonical SMILES: | C1C(NC(=O)NC1=O)C(=O)O |
InChI: | InChI=1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)/t2-/m0/s1 |
InChI Key: | UFIVEPVSAGBUSI-REOHCLBHSA-N |
Purity: | 98.0% |
Density: | 1.523 g/cm3 |
Appearance: | Solid |
MDL: | MFCD00085339 |
LogP: | -0.67330 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021175200-A1 | Ferroptosis inhibitorsâ€"diarylamine para-acetamides | 20200302 |
CN-111289638-A | Application of serum metabolism marker in preparation of diabetic nephropathy early diagnosis reagent and kit | 20200123 |
WO-2021085582-A1 | Pyrazine derivative or salt thereof, and use of same | 20191031 |
WO-2020259714-A1 | Method for preparing degarelix | 20190625 |
WO-2020225095-A1 | Masp inhibitory compounds and uses thereof | 20190507 |
PMID | Publication Date | Title | Journal |
22692683 | 20120915 | Miller (Genee-Wiedemann) syndrome represents a clinically and biochemically distinct subgroup of postaxial acrofacial dysostosis associated with partial deficiency of DHODH | Human molecular genetics |
22580100 | 20120801 | Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii | Molecular and biochemical parasitology |
22509135 | 20120101 | Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation | PLoS biology |
21986535 | 20111028 | Site directed spin labeling studies of Escherichia coli dihydroorotate dehydrogenase N-terminal extension | Biochemical and biophysical research communications |
21912516 | 20110801 | Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum | PLoS biology |
Complexity: | 225 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 158.03275668 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 158.03275668 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 95.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1.5 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS