4-(Trifluoromethyl)imidazole - CAS 33468-69-8

Catalog:	BB021727
Product Name:	4-(Trifluoromethyl)imidazole
CAS:	33468-69-8
Synonyms:	5-(trifluoromethyl)-1H-imidazole; 5-(trifluoromethyl)-1H-imidazole

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	5-(trifluoromethyl)-1H-imidazole
Description:	4-(Trifluoromethyl)imidazole (CAS# 33468-69-8) is used as a reagent used in the synthesis of 3-substituted 2-aminopyridines via displacement of 3-fluoro-2-nitropyridine.
Molecular Weight:	136.08
Molecular Formula:	C4H3F3N2
Canonical SMILES:	C1=C(NC=N1)C(F)(F)F
InChI:	InChI=1S/C4H3F3N2/c5-4(6,7)3-1-8-2-9-3/h1-2H,(H,8,9)
InChI Key:	DFLGRTIPTPCKPJ-UHFFFAOYSA-N
Boiling Point:	224.7 ℃ at 760 mmHg
Density:	1.44 g/cm³
MDL:	MFCD08458860
LogP:	1.42850

Publication Number	Title	Priority Date
WO-2021188880-A1	Benzenesulfonamide derivatives as trap1 modulators and uses thereof	20200320
CN-113072542-A	ROR gamma t inhibitor and preparation method and application thereof	20200106
WO-2021139595-A1	RORÎ³T INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF	20200106
CN-109761906-A	A kind of substituted imidazole formate ester derivative and application thereof	20190302
US-2020269194-A1	Porous membrane containing metal-organic frameworks	20190226

PMID	Publication Date	Title	Journal
18225569	20071101	Quantitative structure-activity relationship analysis of 4-trifluoromethylimidazole derivatives with the concept of absolute hardness	Anticancer research
18225572	20071101	Tumor-specific cytotoxic activity and type of cell death induced by 4-trifluoromethylimidazoles in human oral squamous cell carcinoma cell lines	Anticancer research

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Imidazoles

[54004-47-6]
1-Tetradecylimidazole
[97403-83-3]
3-Allyl-1-methyl-2-thioxoimidazolidin-4-one
[1692391-54-0]
Ethyl 1-propyl-1H-imidazole-2-carboxylate
[1011398-11-0]
Ethyl 2-(1H-imidazol-1-yl)butanoate
[63875-06-9]
1-Methyl-2-phenyl-4-(trifluoromethyl)-1H-imidazole
[1855906-95-4]
N-Benzyl-1-(1-ethyl-4-methyl-1H-imidazol-2-yl)methanamine dihydrochloride

Customers Also Viewed

[63528-29-0]
Ethyl(2-methylpropyl)amine hydrochloride
[30879-49-3]
2'-Nitro-5'-hydroxyacetophenone
[35153-16-3]
(Z)-10-Tetradecenyl Acetate
[891016-02-7]
ML-SI3
[6315-52-2]
Ethylene di(p-toluenesulfonate)
[3735-92-0]
Methyl dimethyldithiocarbamate

INDUSTRY LEADERS TRUST OUR PRODUCTS

Phone

US & Canada (Toll free):

UK:

International:

E-mail & Fax

E-mail:

Fax:

Address

USA:

UK:

Our Products

Inquiry Basket

Loading ......

Delete selected Go to checkout

GHS Hazard Statement:	H302 (96.97%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	101
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	136.02483259
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	136.02483259
Rotatable Bond Count:	0
Topological Polar Surface Area:	28.7 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1