4-Methoxycinnamic acid, predominantly trans - CAS 830-09-1
Catalog: |
BB036949 |
Product Name: |
4-Methoxycinnamic acid, predominantly trans |
CAS: |
830-09-1 |
Synonyms: |
(E)-3-(4-methoxyphenyl)prop-2-enoic acid |
IUPAC Name: | (E)-3-(4-methoxyphenyl)prop-2-enoic acid |
Description: | p-MCA exerted antihyperglycemic/hypoglycemic effect by stimulating insulin secretion from pancreas and could be developed into a new potential for therapeutic agent used in type 2 diabetic patients. |
Molecular Weight: | 178.18 |
Molecular Formula: | C10H10O3 |
Canonical SMILES: | COC1=CC=C(C=C1)C=CC(=O)O |
InChI: | InChI=1S/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-4+ |
InChI Key: | AFDXODALSZRGIH-QPJJXVBHSA-N |
Boiling Point: | 317 °C |
Melting Point: | 173-175 °C |
Purity: | 95 % |
Density: | 1.195 g/cm3 |
Appearance: | White, amorphous, granular powder. |
Storage: | Store in a cool, dry place. Keep container closed when not in use. |
MDL: | MFCD00004398 |
LogP: | 1.79300 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
22766765 | 20121001 | Duodenal calcium transporter mRNA expression in stressed male rats treated with diazepam, fluoxetine, reboxetine, or venlafaxine | Molecular and cellular biochemistry |
22767601 | 20120824 | Alternative pathways for association and dissociation of the calmodulin-binding domain of plasma membrane Ca(2+)-ATPase isoform 4b (PMCA4b) | The Journal of biological chemistry |
22733819 | 20120817 | Distinct regulation of cytoplasmic calcium signals and cell death pathways by different plasma membrane calcium ATPase isoforms in MDA-MB-231 breast cancer cells | The Journal of biological chemistry |
22704985 | 20120710 | A novel role for Bcl-2 in regulation of cellular calcium extrusion | Current biology : CB |
22713297 | 20120619 | Painful nerve injury increases plasma membrane Ca2+-ATPase activity in axotomized sensory neurons | Molecular pain |
Complexity: | 190 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 1 |
Exact Mass: | 178.062994177 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 178.062994177 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 46.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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