4-Hydroxybenzyl alcohol - CAS 623-05-2
Catalog: |
BB031517 |
Product Name: |
4-Hydroxybenzyl alcohol |
CAS: |
623-05-2 |
Synonyms: |
4-(hydroxymethyl)phenol |
Application: |
antiangiogenesis; anti-inflammatory; |
IUPAC Name: | 4-(hydroxymethyl)phenol |
Description: | 4-Hydroxybenzyl alcohol comes from the herbs of Cistanche deserticola Ma. It exhibits beneficial effects in cerebral ischemic injury, which has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. |
Molecular Weight: | 124.14 |
Molecular Formula: | C7H8O2 |
Canonical SMILES: | C1=CC(=CC=C1CO)O |
InChI: | InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2 |
InChI Key: | BVJSUAQZOZWCKN-UHFFFAOYSA-N |
Boiling Point: | 251-253 °C |
Melting Point: | 124.5 °C |
Purity: | 99 % |
Density: | 1.22 g/cm3 |
Solubility: | 6700 mg/L at 20 °C (exp) |
Appearance: | Powder |
MDL: | MFCD00004658 |
LogP: | 0.88450 |
Quality Standard: | Enterprise Standard |
Vapor Pressure: | 0.000825 [mmHg] |
GHS Hazard Statement: | H315 (28.92%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
30273962 | 20181201 | p-Hydroxybenzyl alcohol inhibits four obesity-related enzymes in vitro | Journal of biochemical and molecular toxicology |
22257859 | 20120601 | The implication of mediators for enhancement of laccase oxidation of sulfonamide antibiotics | Bioresource technology |
22155394 | 20120131 | Modulation of LPS-stimulated neuroinflammation in BV-2 microglia by Gastrodia elata: 4-hydroxybenzyl alcohol is the bioactive candidate | Journal of ethnopharmacology |
22470321 | 20120101 | Novel chalcone-based fluorescent human histamine h(3) receptor ligands as pharmacological tools | Frontiers in systems neuroscience |
21995752 | 20111013 | Isolation and characterization of novel bacterial strains exhibiting ligninolytic potential | BMC biotechnology |
Complexity: | 75 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 124.052429494 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 124.052429494 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 40.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.2 |
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