4-Fluorobenzenesulfonyl chloride - CAS 349-88-2
Catalog: |
BB022388 |
Product Name: |
4-Fluorobenzenesulfonyl chloride |
CAS: |
349-88-2 |
Synonyms: |
4-fluorobenzenesulfonyl chloride |
IUPAC Name: | 4-fluorobenzenesulfonyl chloride |
Description: | 4-Fluorobenzenesulfonyl chloride (CAS# 349-88-2) is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR. |
Molecular Weight: | 194.61 |
Molecular Formula: | C6H4ClFO2S |
Canonical SMILES: | C1=CC(=CC=C1F)S(=O)(=O)Cl |
InChI: | InChI=1S/C6H4ClFO2S/c7-11(9,10)6-3-1-5(8)2-4-6/h1-4H |
InChI Key: | BFXHJFKKRGVUMU-UHFFFAOYSA-N |
Boiling Point: | 95-96 °C (2 mmHg) |
Melting Point: | 33-35 °C |
Purity: | 95 % |
Density: | 1.493 g/cm3 |
Appearance: | White to light brown crystalline low melting mass |
Storage: | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
MDL: | MFCD00007438 |
LogP: | 2.83400 |
GHS Hazard Statement: | H302 (37.25%): Harmful if swallowed [Warning Acute toxicity, oral]; H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P363, P405, and P501 |
Signal Word: | Danger |
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PMID | Publication Date | Title | Journal |
22589956 | 20120401 | 4-(4-Fluoro-benzene-sulfonamido)-phenyl 4-fluoro-benzene-sulfonate | Acta crystallographica. Section E, Structure reports online |
21915407 | 20120107 | Application of the dissociative electron transfer theory and its extension to the case of in-cage interactions in the electrochemical reduction of arene sulfonyl chlorides | Physical chemistry chemical physics : PCCP |
19334689 | 20090602 | Peptide surface modification of P(HEMA-co-MMA)-b-PIB-b-P(HEMA-co-MMA) block copolymers | Langmuir : the ACS journal of surfaces and colloids |
Complexity: | 213 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 193.9604564 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 193.9604564 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 42.5 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2 |
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