4-Fluoro-2-(1H-pyrazol-3-yl)phenol - CAS 288401-64-9

Catalog:	BB019987
Product Name:	4-Fluoro-2-(1H-pyrazol-3-yl)phenol
CAS:	288401-64-9
Synonyms:	4-fluoro-2-(1H-pyrazol-5-yl)phenol

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	4-fluoro-2-(1H-pyrazol-5-yl)phenol
Description:	4-Fluoro-2-(1H-pyrazol-3-yl)phenol (CAS# 288401-64-9) is a useful research chemical.
Molecular Weight:	178.16
Molecular Formula:	C9H7FN2O
Canonical SMILES:	C1=CC(=C(C=C1F)C2=CC=NN2)O
InChI:	InChI=1S/C9H7FN2O/c10-6-1-2-9(13)7(5-6)8-3-4-11-12-8/h1-5,13H,(H,11,12)
InChI Key:	QKAHKTLLEHWJPY-UHFFFAOYSA-N
Boiling Point:	206.3 °C at 760 mmHg
Density:	1.36 g/cm³
MDL:	MFCD00104658
LogP:	1.92140

Publication Number	Title	Priority Date
CA-2722159-A1	Substituted phenylimidazole compounds and their use as ido inhibitors	20080424
CA-2722159-C	Substituted phenylimidazole compounds and their use as ido inhibitors	20080424
EP-2291187-A2	Ido inhibitors	20080424
EP-2291187-B1	Ido inhibitors	20080424
US-2011136796-A1	IDO Inhibitors	20080424

PMID	Publication Date	Title	Journal
20580138	20100901	Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: pharmacophore modeling and molecular docking studies	European journal of medicinal chemistry
18665584	20080828	Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase	Journal of medicinal chemistry

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Fluorinated Building Blocks

[1427357-61-6]
6-Fluoro-[1,2,4]triazolo[1,5-a]pyridine
[1946823-77-3]
[1,4-Dimethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methanol
[151585-93-2]
2-Amino-6-fluorobenzaldehyde
[1597-32-6]
2-Amino-6-fluoropyridine
[459836-92-1]
3,6-Difluoro-2-methylbenzoic acid
[150517-77-4]
3-Fluoro-5-(trifluoromethyl)benzylamine

Other Pyrimidines

[2367-82-0]
1,2,3,5-Tetrafluorobenzene
[1183749-69-0]
2-(pyrimidin-2-yloxy)phenol
[246847-98-3]
2-Amino-5-chloro-3-fluoropyridine
[1192570-20-9]
2-Morpholino-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethanamine
[672-45-7]
6-(Trifluoromethyl)uracil
[944580-98-7]
8-(Trifluoromethyl)imidazo[1,2-a]pyridine

Pyrazoles

[1006473-17-1]
[(2,3-Difluorophenyl)methyl][(1,3-dimethylpyrazol-4-yl)methyl]amine
[1946823-77-3]
[1,4-Dimethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methanol
[1281984-38-0]
1-Cyclopentyl-3,5-dinitro-1H-pyrazole
[957292-12-5]
2-(3-Cyclopropyl-1H-pyrazol-1-yl)acetic acid
[1184994-08-8]
2,2-Dimethyl-1-pyrazol-1-ylmethyl-propylamine hydrochloride
[1005626-64-1]
3-(1,3-Dimethylpyrazol-4-yl)-5-[(1-methylpyrazol-4-yl)methylidene]-2-sulfanylideneimidazolidin-4-one

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	179
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	178.05424101
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	178.05424101
Rotatable Bond Count:	1
Topological Polar Surface Area:	48.9 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.6