4-Chloro-7-methylquinoline - CAS 63136-61-8
Catalog: |
BB032023 |
Product Name: |
4-Chloro-7-methylquinoline |
CAS: |
63136-61-8 |
Synonyms: |
4-chloro-7-methylquinoline |
IUPAC Name: | 4-chloro-7-methylquinoline |
Description: | 4-Chloro-7-methylquinoline (CAS# 63136-61-8) is a reagent in the synthesis of certain 4-aminoquinoline derivatives used as antimalarials. |
Molecular Weight: | 177.63 |
Molecular Formula: | C10H8ClN |
Canonical SMILES: | CC1=CC2=NC=CC(=C2C=C1)Cl |
InChI: | InChI=1S/C10H8ClN/c1-7-2-3-8-9(11)4-5-12-10(8)6-7/h2-6H,1H3 |
InChI Key: | SLBWENCMEQRYEG-UHFFFAOYSA-N |
Boiling Point: | 275.6 °C at 760 mmHg |
Purity: | 95 % |
Density: | 1.225 g/cm3 |
LogP: | 3.19660 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-111039942-A | Nitrogen-containing heterocyclic compound, and preparation method, pharmaceutical composition and application thereof | 20181012 |
AU-2016371014-A1 | Polycyclic TLR7/8 antagonists and use thereof in the treatment of immune disorders | 20151217 |
CA-3005766-A1 | Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders | 20151217 |
EP-3390389-A1 | Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders | 20151217 |
TW-201730175-A | TLR7/8 antagonist and its use | 20151217 |
Complexity: | 160 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 177.0345270 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 177.0345270 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 12.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.5 |
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