4-Chloro-6-hydroxypyrimidine - CAS 4765-77-9
Catalog: |
BB026355 |
Product Name: |
4-Chloro-6-hydroxypyrimidine |
CAS: |
4765-77-9 |
Synonyms: |
6-Chloro-4(1H)-Pyrimidinone; 6-Chloro-4(3H)-pyrimidinone; 6-chloro-4-Pyrimidinol; 4-Chloropyrimidin-6-one; NSC 618279 |
IUPAC Name: | 4-chloro-1H-pyrimidin-6-one |
Description: | 4-Chloro-6-hydroxypyrimidine is a compound useful in organic synthesis. |
Molecular Weight: | 130.53 |
Molecular Formula: | C4H3ClN2O |
Canonical SMILES: | C1=C(N=CNC1=O)Cl |
InChI: | InChI=1S/C4H3ClN2O/c5-3-1-4(8)7-2-6-3/h1-2H,(H,6,7,8) |
InChI Key: | AXFABVAPHSWFMD-UHFFFAOYSA-N |
Boiling Point: | 199.42 ℃ at 760 mmHg |
Melting Point: | 190-194 ℃ |
Purity: | 98 % |
Density: | 1.553 g/cm3 |
Solubility: | DMSO; Water |
Appearance: | Off-white to pale yellowish solid |
Storage: | Refrigerator |
MDL: | MFCD00233957 |
LogP: | 0.83560 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2020250123-A1 | Prmt5 inhibitors | 20190610 |
CN-111909099-A | Pyrimidine hydrazone derivatives, and preparation method and application thereof | 20190507 |
WO-2020163544-A1 | Methods and compositions for modulating splicing | 20190206 |
WO-2020115501-A1 | Pharmaceutical compounds and their use as inhibitors of ubiquitin specific protease 19 (usp19) | 20181206 |
CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 20181206 |
PMID | Publication Date | Title | Journal |
21581841 | 20090108 | 1,4-Bis(6-chloro-pyrimidin-4-yl-oxy)benzene | Acta crystallographica. Section E, Structure reports online |
Complexity: | 173 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 129.9933904 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 129.9933904 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 41.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.1 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Alcohols and Derivatives
Other Pyrimidines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS