4-Chloro-1-hydrazinophthalazine - CAS 51935-42-3

Name: 4-Chloro-1-hydrazinophthalazine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB055580
Product Name:	4-Chloro-1-hydrazinophthalazine
CAS:	51935-42-3
Synonyms:	1-Chloro-4-hydrazinophthalazine; 1-Chloro-4-hydrazinylphthalazine; 1-Hydrazino-4-chlorophthalazine

Technical Data

IUPAC Name:	(4-chlorophthalazin-1-yl)hydrazine
Description:	4-Chloro-1-hydrazinophthalazine is an intermediate in the synthesis of novel 1,2,4-triazolo[3,4-a]phthalazine derivatives with anticancer activities.
Molecular Weight:	194.62
Molecular Formula:	C8H7ClN4
Canonical SMILES:	C1=CC=C2C(=C1)C(=NN=C2Cl)NN
InChI:	InChI=1S/C8H7ClN4/c9-7-5-3-1-2-4-6(5)8(11-10)13-12-7/h1-4H,10H2,(H,11,13)
InChI Key:	UQTJGZYAFKMABR-UHFFFAOYSA-N
Solubility:	DMSO, Methanol:Water
Appearance:	Light Yellow Powder
References:	Hameed, P. S., et al. J. Med. Chem., 57, 5702 (2014).

GHS Hazard Statement:	H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-110845457-A	Usnic acid derivative, preparation method thereof and application of usnic acid derivative in Alzheimer disease medicine	20191022
WO-2019133666-A1	Triazolophthalazine compounds, use as anti-human immunodeficiency virus inhibitors of hiv vif-dependent degradation of apobec3	20171228
US-2019298717-A1	Hydralazine and Active Derivatives Thereof for Neuronal Cell Survival and Regeneration	20160314
WO-2017160864-A1	Hydralazine and active derivatives thereof for neuronal cell survival and regeneration	20160314
US-2020165253-A1	Phthalazine Derivatives, Preparation Method, Pharmaceutical Composition and Usage Thereof	20151208
WO-2017097217-A1	Phthalazine derivatives, and preparation method, pharmaceutical composition and use thereof	20151208
EP-3025716-A1	Substance for treatment or relief of pain	20120214
EP-3025716-B1	Substance for treatment or relief of pain	20120214
JP-2015509935-A	Substances that treat and relieve pain	20120214
JP-6061956-B2	Substances that treat and relieve pain	20120214

Complexity:	178
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	194.0359239
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	194.0359239
Rotatable Bond Count:	1
Topological Polar Surface Area:	63.8Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	1.6