4-Bromo-1-cyclopropyl-1H-pyrazole - CAS 1151802-23-1
Catalog: |
BB003501 |
Product Name: |
4-Bromo-1-cyclopropyl-1H-pyrazole |
CAS: |
1151802-23-1 |
Synonyms: |
4-bromo-1-cyclopropylpyrazole; 4-bromo-1-cyclopropylpyrazole |
IUPAC Name: | 4-bromo-1-cyclopropylpyrazole |
Description: | 4-Bromo-1-cyclopropyl-1H-pyrazole (CAS# 1151802-23-1) is used in the treatment of cancer as a triazolopyridazine c-Met kinase inhibitor. |
Molecular Weight: | 187.04 |
Molecular Formula: | C6H7BrN2 |
Canonical SMILES: | C1CC1N2C=C(C=N2)Br |
InChI: | InChI=1S/C6H7BrN2/c7-5-3-8-9(4-5)6-1-2-6/h3-4,6H,1-2H2 |
InChI Key: | PCWRBBLXAOCSQC-UHFFFAOYSA-N |
Storage: | Sealed in dry, 2-8 °C |
LogP: | 1.98050 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021080929-A1 | N-(heteroaryl) quinazolin-2-amine derivatives as lrrk2 inhibitors, pharmaceutical compositions, and uses thereof | 20191025 |
CN-112457295-A | Compound with Axl and c-Met kinase inhibitory activity and preparation and application thereof | 20190906 |
WO-2021043217-A1 | Compound having axl and c-met kinase inhibitory activity, preparation thereof and application thereof | 20190906 |
US-2020377510-A1 | Derivatives of piperlongumine and uses thereof | 20190530 |
WO-2020112706-A1 | 7-, 8-, and 10-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | 20181130 |
Complexity: | 114 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 185.97926 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 185.97926 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 17.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.4 |
-
Catalog: BB052023
(1-Cyclopentyl-1H-pyrazol-5-yl)acetic acid
Detail
-
Catalog: BB045655
((5-[(4-Chloro-3-methyl-1H-pyrazol-1-yl)methyl]-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetic acid
Detail
-
Catalog: BB051001
(1E)-1-[1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]ethanone oxime
Detail
-
Catalog: BB051531
(1E)-1-[1-(2,2,2-Trifluoroethyl)-1H-pyrazol-3-yl]ethanone oxime
Detail
-
Catalog: BB050668
(1-(2,2,2-Trifluoroethyl)-1H-pyrazol-4-yl)methanol
Detail
-
Catalog: BB045656
([5-(1-Ethyl-1H-pyrazol-3-yl)-4-(tetrahydrofuran-2-ylmethyl)-4H-1,2,4-triazol-3-yl]thio)acetic acid
Detail
-
Catalog: BB045227
(1E)-N-Hydroxy-1-phenyl-2-(1H-pyrazol-1-yl)ethanimine
Detail
-
Catalog: BB051687
(1-(2,2,2-Trifluoroethyl)-1H-pyrazol-5-yl)methanol
Detail
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Pyrazoles
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS