4-(Benzhydryloxy)piperidine - CAS 58258-01-8

Catalog:	BB029990
Product Name:	4-(Benzhydryloxy)piperidine
CAS:	58258-01-8
Synonyms:	4-(diphenylmethyl)oxypiperidine; 4-benzhydryloxypiperidine

Technical Data

Patents

Literatures

Computed Properties

IUPAC Name:	4-benzhydryloxypiperidine
Description:	A metabolite of Ebastine.
Molecular Weight:	267.37
Molecular Formula:	C18H21NO
Canonical SMILES:	C1CNCCC1OC(C2=CC=CC=C2)C3=CC=CC=C3
InChI:	InChI=1S/C18H21NO/c1-3-7-15(8-4-1)18(16-9-5-2-6-10-16)20-17-11-13-19-14-12-17/h1-10,17-19H,11-14H2
InChI Key:	OQAOREVBRZVXDS-UHFFFAOYSA-N
Boiling Point:	383.5 °C at 760 mmHg
Density:	1.09 g/cm³
MDL:	MFCD06659472
LogP:	3.87340

Publication Number	Title	Priority Date
CN-112574097-A	Preparation method of Ebastine and fumarate thereof	20201221
CN-110988215-A	Method for detecting related substances in ebastine	20191231
CN-109593058-B	Preparation method of ebastine	20190123
DE-202011000756-U1	Ebastins, non-micronised ebastine particles and pharmaceutical compositions comprising ebastines	20110331
WO-2012076919-A1	Process of preparing ebastine	20101211

PMID	Publication Date	Title	Journal
21410688	20110801	Myocardial pharmacokinetics of ebastine, a substrate for cytochrome P450 2J, in rat isolated heart	British journal of pharmacology
16896065	20061101	Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A	Drug metabolism and disposition: the biological fate of chemicals
16842392	20060801	The effect of CYP2J2, CYP3A4, CYP3A5 and the MDR1 polymorphisms and gender on the urinary excretion of the metabolites of the H-receptor antihistamine ebastine: a pilot study	British journal of clinical pharmacology
15556518	20041225	Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Piperidines

[1035840-45-9]
1-(5-Methoxy-1,3-benzoxazol-2-yl)piperidine-3-carboxylic acid
[1005629-22-0]
Ethyl 1-((1-ethyl-3-methyl-1H-pyrazol-4-yl)sulfonyl)piperidine-3-carboxylate
[349625-89-4]
Ethyl 1-(methylsulfonyl)piperidine-3-carboxylate
[217487-18-8]
Ethyl 1-(methylsulfonyl)piperidine-4-carboxylate
[610259-52-4]
Ethyl 1-(thiophen-2-ylsulfonyl)piperidine-3-carboxylate
[1172760-90-5]
Ethyl 1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]piperidine-3-carboxylate

Customers Also Viewed

[2555-49-9]
Ethyl phenoxyacetate
[44994-28-7]
N,N,N',N'-Tetramethyl-1,5-pentanediamine
[6315-52-2]
Ethylene di(p-toluenesulfonate)
[94086-78-9]
Isopropyl 4-[4-[N,N-bis(2-hydroxyethyl)amino]phenyl]butyrate
[33229-34-4]
2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol
[55382-52-0]
Methyl Divarinolcarboxylate

INDUSTRY LEADERS TRUST OUR PRODUCTS

Phone

US & Canada (Toll free):

UK:

International:

E-mail & Fax

E-mail:

Fax:

Address

USA:

UK:

Our Products

Inquiry Basket

Loading ......

Delete selected Go to checkout

Complexity:	245
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	267.162314293
Formal Charge:	0
Heavy Atom Count:	20
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	1
Isotope Atom Count:	0
Monoisotopic Mass:	267.162314293
Rotatable Bond Count:	4
Topological Polar Surface Area:	21.3
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	3.4