4-Amino-2-methyl-2H-indazole - CAS 82013-51-2
Catalog: |
BB036742 |
Product Name: |
4-Amino-2-methyl-2H-indazole |
CAS: |
82013-51-2 |
Synonyms: |
2-methyl-4-indazolamine; 2-methylindazol-4-amine |
IUPAC Name: | 2-methylindazol-4-amine |
Description: | 4-Amino-2-methyl-2H-indazole (CAS# 82013-51-2) is used as a reagent in organic synthesis including that of 4-(2-imidazolin-2-ylamino-2-methylindazole-HCl which display antihypertensive activity. It is also used in the synthesis of spleen tyrosine kinase (Syk) inhibitors that display high potency in the presence of blood. |
Molecular Weight: | 147.18 |
Molecular Formula: | C8H9N3 |
Canonical SMILES: | CN1C=C2C(=N1)C=CC=C2N |
InChI: | InChI=1S/C8H9N3/c1-11-5-6-7(9)3-2-4-8(6)10-11/h2-5H,9H2,1H3 |
InChI Key: | RMCAMILOUFSNOR-UHFFFAOYSA-N |
Boiling Point: | 354.8 °C at 760 mmHg |
Density: | 1.27 g/cm3 |
MDL: | MFCD09870044 |
LogP: | 1.73670 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
TW-201945355-A | Condensed cyclic urea derivatives as CRHR2 antagonists | 20180409 |
WO-2019198692-A1 | Fused cyclic urea derivatives as crhr2 antagonist | 20180409 |
CN-111868037-A | Fused cyclic urea derivatives as CRHR2 antagonists | 20180409 |
KR-20200135834-A | Condensed cyclic urea derivatives as CRHR2 antagonists | 20180409 |
BR-112020020708-A2 | CYCLIC UREA FUSED DERIVATIVES AS CRHR2 ANTAGONIST | 20180409 |
Complexity: | 148 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 147.079647300 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 147.079647300 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 43.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.9 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Indazoles
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS