4-Amino-2-fluoro-N-methylbenzamide - CAS 915087-25-1
Catalog: |
BB040222 |
Product Name: |
4-Amino-2-fluoro-N-methylbenzamide |
CAS: |
915087-25-1 |
Synonyms: |
4-amino-2-fluoro-N-methylbenzamide; 4-amino-2-fluoro-N-methylbenzamide |
IUPAC Name: | 4-amino-2-fluoro-N-methylbenzamide |
Description: | 4-Amino-2-fluoro-N-methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors. |
Molecular Weight: | 168.17 |
Molecular Formula: | C8H9FN2O |
Canonical SMILES: | CNC(=O)C1=C(C=C(C=C1)N)F |
InChI: | InChI=1S/C8H9FN2O/c1-11-8(12)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3,(H,11,12) |
InChI Key: | XOKAXPQJUODMSH-UHFFFAOYSA-N |
LogP: | 1.92350 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P272, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P333+P313, P337+P313, P363, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2021117062-A1 | Process for the preparation of 4-[7-(6-Cyano-5-trifluoromethylpyridin-3-yl)-8-oxo-6-thioxo-5,7- diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzamide and its polymorphs | 20191211 |
WO-2021033098-A1 | Process for the preparation of apalutamide | 20190822 |
CN-112047888-A | Method for synthesizing enzalutamide | 20190605 |
WO-2019229625-A1 | Process for the preparation of apalutamide | 20180530 |
CN-112218856-A | Process for preparing apaluramine | 20180530 |
Complexity: | 174 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 168.06989108 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 168.06989108 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 55.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.6 |
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