4-Amino-2-[1-(cyclopropylsulfonyl)-4-pyrazolyl]pyrimidine - CAS 1612174-02-3
Catalog: |
BB011713 |
Product Name: |
4-Amino-2-[1-(cyclopropylsulfonyl)-4-pyrazolyl]pyrimidine |
CAS: |
1612174-02-3 |
Synonyms: |
2-(1-cyclopropylsulfonyl-4-pyrazolyl)-4-pyrimidinamine; 2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-amine |
IUPAC Name: | 2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-amine |
Description: | 4-Amino-2-[1-(cyclopropylsulfonyl)-4-pyrazolyl]pyrimidine (CAS# 1612174-02-3 ) is a useful research chemical. |
Molecular Weight: | 265.29 |
Molecular Formula: | C10H11N5O2S |
Canonical SMILES: | C1CC1S(=O)(=O)N2C=C(C=N2)C3=NC=CC(=N3)N |
InChI: | InChI=1S/C10H11N5O2S/c11-9-3-4-12-10(14-9)7-5-13-15(6-7)18(16,17)8-1-2-8/h3-6,8H,1-2H2,(H2,11,12,14) |
InChI Key: | LGZCTXYBYNYHEJ-UHFFFAOYSA-N |
Publication Number | Title | Priority Date |
EP-3052494-A1 | Azaindazole compounds as inhibitors of t790m containing egfr mutants | 20130628 |
EP-3052494-B1 | Azaindazole compounds as inhibitors of t790m containing egfr mutants | 20130628 |
US-2016257682-A1 | Azaindazole compounds as inhibitors of t790m containing egfr mutants | 20130628 |
US-9951064-B2 | Azaindazole compounds as inhibitors of T790M containing EGFR mutants | 20130628 |
WO-2014210354-A1 | Azaindazole compounds as inhibitors of t790m containing egfr mutants | 20130628 |
Complexity: | 405 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 265.06334578 |
Formal Charge: | 0 |
Heavy Atom Count: | 18 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 265.06334578 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 112 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.1 |
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