4-Amino-1H-imidazo[4,5-c]quinoline - CAS 132207-04-6
Catalog: |
BB007559 |
Product Name: |
4-Amino-1H-imidazo[4,5-c]quinoline |
CAS: |
132207-04-6 |
Synonyms: |
3H-imidazo[4,5-c]quinolin-4-amine; 3H-imidazo[4,5-c]quinolin-4-amine |
IUPAC Name: | 3H-imidazo[4,5-c]quinolin-4-amine |
Description: | 3H-Imidazo[4,5-c]quinolin-4-amine can be used as reactant/reagent in preparation of imidazoquinolinamines as immune response modifiers. |
Molecular Weight: | 184.20 |
Molecular Formula: | C10H8N4 |
Canonical SMILES: | C1=CC=C2C(=C1)C3=C(C(=N2)N)NC=N3 |
InChI: | InChI=1S/C10H8N4/c11-10-9-8(12-5-13-9)6-3-1-2-4-7(6)14-10/h1-5H,(H2,11,14)(H,12,13) |
InChI Key: | HQBUPOAKJGJGCD-UHFFFAOYSA-N |
LogP: | 0.00000 |
Publication Number | Title | Priority Date |
US-2021275683-A1 | Nectin-4 antibody conjugates and uses thereof | 20200221 |
WO-2021168274-A1 | Nectin-4 antibody conjugates and uses thereof | 20200221 |
WO-2021067644-A1 | Combination therapy with immune stimulatory conjugates | 20191001 |
CN-110327326-A | Isorhamnetin preparation for preventing and treating the drug of psoriasis, the application in health care product | 20190812 |
WO-2021007160-A1 | Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy | 20190705 |
PMID | Publication Date | Title | Journal |
19284749 | 20090409 | Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor | Journal of medicinal chemistry |
18615273 | 20090301 | Allosteric modulation of adenosine receptors | Purinergic signalling |
19077268 | 20081212 | Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000 | BMC pharmacology |
16722654 | 20060601 | Structure-activity relationships of new 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric enhancers of the A3 adenosine receptor | Journal of medicinal chemistry |
15887957 | 20050519 | Synthesis and structure-activity-relationships of 1H-imidazo[4,5-c]quinolines that induce interferon production | Journal of medicinal chemistry |
Complexity: | 220 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 184.074896272 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 184.074896272 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 67.6 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.4 |
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Amines and Anilines
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