4-(4-Fluorophenyl)-1H-imidazole - CAS 65020-70-4
Catalog: |
BB032616 |
Product Name: |
4-(4-Fluorophenyl)-1H-imidazole |
CAS: |
65020-70-4 |
Synonyms: |
5-(4-fluorophenyl)-1H-imidazole |
IUPAC Name: | 5-(4-fluorophenyl)-1H-imidazole |
Description: | 4-(4-Fluorophenyl)-1H-imidazole (CAS# 65020-70-4) is a useful research chemical. |
Molecular Weight: | 162.16 |
Molecular Formula: | C9H7FN2 |
Canonical SMILES: | C1=CC(=CC=C1C2=CN=CN2)F |
InChI: | InChI=1S/C9H7FN2/c10-8-3-1-7(2-4-8)9-5-11-6-12-9/h1-6H,(H,11,12) |
InChI Key: | QYDAFWKRBZYBOB-UHFFFAOYSA-N |
Appearance: | White to tan solid |
MDL: | MFCD00297041 |
LogP: | 2.21580 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P280, P301+P312, P305+P351+P338, P310, P330, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021105474-A1 | New compounds for treatment of diseases related to dux4 expression | 20191129 |
CN-111936496-A | Use of 4- (1H-imidazol-5-yl) -1H-pyrrolo [2,3-B ] pyridine for the treatment of leukemias, lymphomas and solid tumors | 20180329 |
KR-20200116137-A | 4-(1H-imidazol-5-yl)-1H-pyrrolo[2,3-b]pyridine for use in the treatment of leukemia, lymphoma and solid tumors | 20180329 |
US-2021040086-A1 | 4-(1h- imidazol- 5- yl) -1h-pyrrolo [2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors | 20180329 |
JP-2021517157-A | 4- (1H-imidazol-5-yl) -1H-pyrrolo [2,3-b] pyridine for use in the treatment of leukemia, lymphoma and solid tumors | 20180329 |
PMID | Publication Date | Title | Journal |
18665584 | 20080828 | Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase | Journal of medicinal chemistry |
Complexity: | 144 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 162.05932639 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 162.05932639 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 28.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.8 |
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