4-(4-Fluorobenzyl)piperidine - CAS 92822-02-1
Catalog: |
BB040658 |
Product Name: |
4-(4-Fluorobenzyl)piperidine |
CAS: |
92822-02-1 |
Synonyms: |
4-[(4-fluorophenyl)methyl]piperidine; 4-[(4-fluorophenyl)methyl]piperidine |
IUPAC Name: | 4-[(4-fluorophenyl)methyl]piperidine |
Description: | 4-(4-Fluorobenzyl)piperidine (CAS# 92822-02-1) is a building block for the synthesis of many pharmaceutical compounds. 4-(4-Fluorobenzyl)piperidine has been used as a reactant for the synthesis of chemokine antagonists and non-peptidic β-secretase inhibitors. |
Molecular Weight: | 193.26 |
Molecular Formula: | C12H16FN |
Canonical SMILES: | C1CNCCC1CC2=CC=C(C=C2)F |
InChI: | InChI=1S/C12H16FN/c13-12-3-1-10(2-4-12)9-11-5-7-14-8-6-11/h1-4,11,14H,5-9H2 |
InChI Key: | JLAKCHGEEBPDQI-UHFFFAOYSA-N |
Boiling Point: | 285 °C at 760 mmHg |
Density: | 1.044 g/cm3 |
MDL: | MFCD03839825 |
LogP: | 2.69660 |
GHS Hazard Statement: | H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113468132-A | Method and device for carrying out capacity reduction on fragments in block chain system | 20210901 |
CN-113468200-A | Method and device for expanding fragments in block chain system | 20210901 |
CN-113503091-A | Door lock catch closing mechanism | 20210816 |
CN-113418048-A | Precision control proportional valve | 20210730 |
CN-113507482-A | Data secure transmission method, secure transaction method, system, medium, and device | 20210727 |
PMID | Publication Date | Title | Journal |
21453995 | 20110601 | Synthesis, evaluation and metabolic studies of radiotracers containing a 4-(4-[18F]-fluorobenzyl)piperidin-1-yl moiety for the PET imaging of NR2B NMDA receptors | European journal of medicinal chemistry |
17315856 | 20070322 | Application of fragment screening by X-ray crystallography to beta-secretase | Journal of medicinal chemistry |
Complexity: | 158 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 193.126677677 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 193.126677677 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 12 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.6 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Piperidines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS