4-[(4-Chloro-3-fluorophenyl)amino]-6-nitroquinazolin-7-ol - CAS 2475094-95-0

Catalog: BB062341
Product Name: 4-[(4-Chloro-3-fluorophenyl)amino]-6-nitroquinazolin-7-ol
CAS: 2475094-95-0
Synonyms: 4- [(4- Chloro- 3- fluorophenyl) amino] - 6- nitro-7- quinazolinol; Afatinib Impurity
Description:4-[(4-Chloro-3-fluorophenyl)amino]-6-nitroquinazolin-7-ol may be useful in the preparation of lung cancer drugs. It is a related compound of Afatinib (A355300), which is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
Molecular Weight:334.69
Molecular Formula:C14H8ClFN4O3
References:Xiang, F., et al. Faming Zhuanli Shenqing, 32pp. (2020); Schroeder, J., et al. PCT Int. Appl. (2007); Nakao, K., et al. Sci. Rep., 9, 18202 (2019); Ebert, K., et al. PLoS One, 14, 0223225 (2019).

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