4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone - CAS 223801-42-1

Catalog: BB056587
Product Name: 4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone
CAS: 223801-42-1
Synonyms: 4-[3-Methoxy-4-(tetrahydropyranyloxy)phenyl]-2-butanone
4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone
IUPAC Name:4-[3-methoxy-4-(oxan-2-yloxy)phenyl]butan-2-one
Description:4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone is an intermediate used in the synthesis of [6]-Shogaol (S357800), which is an aromatic constituent of ginger and the chain-dehydroxylated analog of [6]-Gingerol. [6]-Shogaol has activity very similar to [6]-Gingerol and produced an inhibition of spontaneous motor activity, antipyretic and analgesic effects, and prolonged hexobarbital-induced sleeping time. [6]-Shogaol also has potent antitussive activity and affected the cortical EEG.
Molecular Weight:278.34
Molecular Formula:C16H22O4
Canonical SMILES:CC(=O)CCC1=CC(=C(C=C1)OC2CCCCO2)OC
InChI:InChI=1S/C16H22O4/c1-12(17)6-7-13-8-9-14(15(11-13)18-2)20-16-5-3-4-10-19-16/h8-9,11,16H,3-7,10H2,1-2H3
InChI Key:XYDOIKWKTCWOCM-UHFFFAOYSA-N
Solubility:Dichloromethane; Ethyl Acetate; Methanol
Appearance:Colorless Oil
References:Suekawa, M. et al. J. Pharm-Dyn., 7, 836 (1984); Yoshikawa, M. et al. Chem. Pharmac. Bull., 40, 2239 (1992).

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