4-(3-Aminophenyl)-2-methylthiazole - CAS 89250-34-0
Catalog: |
BB039393 |
Product Name: |
4-(3-Aminophenyl)-2-methylthiazole |
CAS: |
89250-34-0 |
Synonyms: |
3-(2-methyl-1,3-thiazol-4-yl)aniline |
IUPAC Name: | 3-(2-methyl-1,3-thiazol-4-yl)aniline |
Description: | 4-(3-Aminophenyl)-2-methylthiazole (CAS# 89250-34-0) is a useful reagent for preparation of N-aryltrifluoromethanesulfinimide derivatives. |
Molecular Weight: | 190.26 |
Molecular Formula: | C10H10N2S |
Canonical SMILES: | CC1=NC(=CS1)C2=CC(=CC=C2)N |
InChI: | InChI=1S/C10H10N2S/c1-7-12-10(6-13-7)8-3-2-4-9(11)5-8/h2-6H,11H2,1H3 |
InChI Key: | CPHZPWZSSBCSAH-UHFFFAOYSA-N |
Boiling Point: | 380.6 °C at 760 mmHg |
Density: | 1.219 g/cm3 |
MDL: | MFCD02579873 |
LogP: | 3.28190 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CA-3072698-A1 | Sulfonamide derivatives as stat3 inhibitors for the treatment of proliferative diseases | 20170811 |
EP-3665164-A1 | Sulfonamide derivatives as stat3 inhibitors for the treatment of proliferative diseases | 20170811 |
US-2020216432-A1 | Sulfonamide derivatives as stat3 inhibitors for the treatment of proliferative diseases | 20170811 |
WO-2019030538-A1 | SULFONAMIDE DERIVATIVES AS STAT3 INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | 20170811 |
JP-2020529451-A | Sulfonamide derivatives as STAT3 inhibitors for the treatment of proliferative disorders | 20170811 |
PMID | Publication Date | Title | Journal |
22547662 | 20120701 | Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates | The Journal of antimicrobial chemotherapy |
Complexity: | 174 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 190.05646950 |
Formal Charge: | 0 |
Heavy Atom Count: | 13 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 190.05646950 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 67.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.3 |
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Related Functional Groups
Oxazole/Thiazole
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