4-(2-Hydroxyethyl)morpholine - CAS 622-40-2
Catalog: |
BB031480 |
Product Name: |
4-(2-Hydroxyethyl)morpholine |
CAS: |
622-40-2 |
Synonyms: |
2-morpholin-4-ylethanol |
IUPAC Name: | 2-morpholin-4-ylethanol |
Description: | 4-(2-Hydroxyethyl)morpholine (CAS# 622-40-2) is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary culture/DNA. |
Molecular Weight: | 131.17 |
Molecular Formula: | C6H13NO2 |
Canonical SMILES: | C1COCCN1CCO |
InChI: | InChI=1S/C6H13NO2/c8-4-1-7-2-5-9-6-3-7/h8H,1-6H2 |
InChI Key: | KKFDCBRMNNSAAW-UHFFFAOYSA-N |
Boiling Point: | 223-225 °C |
Melting Point: | -1 °C |
Purity: | 95 % |
Density: | 1.08 g/cm3 |
Appearance: | Clear colourless to yellow liquid |
Storage: | Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. |
MDL: | MFCD00006180 |
LogP: | -0.75120 |
GHS Hazard Statement: | H315 (50.54%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113321269-A | Method for effectively separating organic matters in high-salinity wastewater | 20210601 |
CN-113068577-A | Intensive tomato seedling culture method | 20210405 |
CN-113060843-A | Multifunctional phosphorus-free boiler water treatment agent and application thereof | 20210326 |
CN-112790190-A | Toilet training agent special for cats and dogs and preparation method thereof | 20210220 |
CN-112940011-A | Lysosome targeted ratio type hypochlorous acid fluorescent probe | 20210108 |
PMID | Publication Date | Title | Journal |
21522955 | 20110108 | N-[4-(2-Morpholino-eth-oxy)phen-yl]acetamide monohydrate | Acta crystallographica. Section E, Structure reports online |
21115914 | 20101101 | In vitro cytotoxicity of benzopyranone derivatives with basic side chain against human lung cell lines | Anticancer research |
19128485 | 20090107 | Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue | BMC chemical biology |
17275481 | 20070101 | Noninfectious gastrointestinal (GI) complications of mycophenolic acid therapy: a consequence of local GI toxicity? | Transplantation proceedings |
Complexity: | 71.5 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 131.094628657 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 131.094628657 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 32.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.8 |
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Related Functional Groups
Morpholines/Thiomorpholines
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