(3R,4S)-2-Oxo-3-oxhydryl-4-phenyl-1-boc-azetidine - CAS 155874-22-9

Catalog: BB056708
Product Name: (3R,4S)-2-Oxo-3-oxhydryl-4-phenyl-1-boc-azetidine
CAS: 155874-22-9
Synonyms: (3R,4S)-tert-Butyl 3-hydroxy-2-oxo-4-phenylazetidine-1-carboxylate
Description:(3R,4S)-2-Oxo-3-oxhydryl-4-phenyl-1-boc-azetidine is an intermediate in the preparation of Paclitaxel (P132500), a neoplasm inhibitor used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
Molecular Weight:263.29
Molecular Formula:C14H17NO4
References:Letourneau, P., et. al. J. Cell Biol., 98, 1355 (1984);Manfredi, J., et. al. Pharmacol. Ther., 25, 83 (1984);Danesi, R., et. al. Mol. Pharmacol., 47, 1106 (1995);Markman, M., et. al. Expert. Opin. Pharmacother., 3, 755 (2002);Stone, G., et. al. N. Engl. J. Med., 350, 221 (2004),.

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