(3R)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile

Catalog: BB076821
Product Name: (3R)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile
Synonyms: (R)-1-[(4-Methylphenyl)sulfonyl]-α,α-diphenyl-3-pyrrolidineacetonitrile; (R)-2,2-Diphenyl-2-(1-tosyl-3-pyrrolidinyl)acetonitrile; 2,2-Diphenyl-2-((3S)-1-tosyl-3-pyrrolidinyl)acetonitrile; (R)-2,2-Diphenyl-2-(1-tosylpyrrolidin-3-yl)acetonitrile
Description:(3R)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile is the isomeric pair of (3S)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile, which is a reactant used in the preparation of Darifenacin Hydrobromide (D193400), which is used as a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor.
Molecular Weight:416.54
Molecular Formula:C25H24N2O2S
References:Murthy, M.V., et. al. J. Pharm. Biomed. Anal., 72, 40 (2013); Beaumont, K.C., et al. Xenobiotica, 28, 63 (1998); Chapple, C.R., et al. Expert Opin. Invest. Drugs, 13, 1493 (2004); Haab, F., et al. Eur. Urol., 45, 420 (2004).

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