3-(tert-Butyldimethylsilyloxy)glutaric anhydride - CAS 91424-40-7
Catalog: |
BB040183 |
Product Name: |
3-(tert-Butyldimethylsilyloxy)glutaric anhydride |
CAS: |
91424-40-7 |
Synonyms: |
4-[tert-butyl(dimethyl)silyl]oxyoxane-2,6-dione |
IUPAC Name: | 4-[tert-butyl(dimethyl)silyl]oxyoxane-2,6-dione |
Description: | 3-(tert-Butyldimethylsilyloxy)glutaric anhydride (CAS# 91424-40-7) is an organic building block used in the synthesis of more complex pharmaceutical compounds. It is used for the preparation of the HMG-CoA reductase inhibitor Pitavastatin (P531040). |
Molecular Weight: | 244.36 |
Molecular Formula: | C11H20O4Si |
Canonical SMILES: | CC(C)(C)[Si](C)(C)OC1CC(=O)OC(=O)C1 |
InChI: | InChI=1S/C11H20O4Si/c1-11(2,3)16(4,5)15-8-6-9(12)14-10(13)7-8/h8H,6-7H2,1-5H3 |
InChI Key: | RXAJGRHLLRGVSB-UHFFFAOYSA-N |
Boiling Point: | 302.4 °C at 760 mmHg |
Melting Point: | 79-81 °C |
Purity: | 98 % |
Density: | 1.03 g/cm3 |
Appearance: | White sheet crystalline powder |
MDL: | MFCD00075235 |
LogP: | 2.24040 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
15149187 | 20040501 | A modular approach to the synthesis of new reagents useful in the chemical synthesis of modified DNA probes: derivatives of 3-(tert-butyldimethylsiloxy)glutaric anhydride as versatile building blocks in the synthesis of new phosphoramidites and modified solid supports | Bioconjugate chemistry |
Complexity: | 288 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 244.11308565 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 244.11308565 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 52.6 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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