3-Oxo-4-aza-5α-androst-1-ene-17α-carboxylic Acid Chloride

Catalog: BB058512
Product Name: 3-Oxo-4-aza-5α-androst-1-ene-17α-carboxylic Acid Chloride
Synonyms: 3-Oxo-4-aza-5α-androst-1-ene-17α-carboxoyl Chloride; (4aR,4bS,6aS,7R,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carbonyl Chloride
Description:3-Oxo-4-aza-5α-androst-1-ene-17α-carboxylic Acid Chloride is an intermediate used in the synthesis of Dutasteride α-Dimer (D735015), which is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.
Molecular Weight:335.87
Molecular Formula:C19H26ClNO2
References:Bakshi, R.K., et al. J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al. Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al. Expert Opin. Pharmacother., 6, 311 (2005).

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