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| Description: | 3-Oxo-4-aza-5α-androst-1-ene-17α-carboxylic Acid Chloride is an intermediate used in the synthesis of Dutasteride α-Dimer (D735015), which is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia. |
| Molecular Weight: | 335.87 |
| Molecular Formula: | C19H26ClNO2 |
| References: | Bakshi, R.K., et al. J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al. Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al. Expert Opin. Pharmacother., 6, 311 (2005). |
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