3-O-Ethyl-L-ascorbic acid - CAS 86404-04-8

Catalog:	BB037914
Product Name:	3-O-Ethyl-L-ascorbic acid
CAS:	86404-04-8
Synonyms:	3-O-Ethylascorbic acid; L-Ascorbic acid 3-O-ethyl ether; COS-VCE; ENB-VCE; VC Ethyl; Ethyl Ascorbic Acid; VCE; Vitamin C ethyl ether
Application:	Cosmetic Raw Materials

Catalog	Size	Price	Stock	Quantity
BB037914	1 g	$199	In stock
BB037914	5 g	$319	In stock

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Technical Data

IUPAC Name:	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-ethoxy-4-hydroxy-2H-furan-5-one
Description:	3-O-Ethyl-L-ascorbic acid inhibits tyrosinase activity, inhibits the formation of melanin, restores melanin to colorless, effectively removes freckles and whitens, improves dull skin, and endorses skin elasticity. It has an excellent antioxidant effect in cosmetics and ensures the utilization of vitamin C. Compared to the vitamin C prototype, it is very stable and does not discolor. It has a strong antibacterial and anti-inflammatory effect and fights inflammation caused by sunlight. It enters the dermis, directly participates in the synthesis of collagen, repairs the activity of skin cells, increases collagen, and makes the skin full, elastic, delicate and smooth. It has a lipophilic hydrophilic structure, which is easily absorbed by the skin and can reach the dermis directly. It demonstrates good stability against light exposure as well as resistance to heat, acid-alkali conditions, salt corrosion, and air oxidation.
Molecular Weight:	204.18
Molecular Formula:	C8H12O6
Canonical SMILES:	CCOC1=C(C(=O)OC1C(CO)O)O
InChI:	InChI=1S/C8H12O6/c1-2-13-7-5(11)8(12)14-6(7)4(10)3-9/h4,6,9-11H,2-3H2,1H3/t4-,6+/m0/s1
InChI Key:	ZGSCRDSBTNQPMS-UJURSFKZSA-N
Boiling Point:	551.5±50.0°C at 760 Torr
Melting Point:	116-117.5°C
Purity:	99%
Density:	1.46±0.1 g/cm3
Solubility:	Soluble in Methanol (Slightly), Water (Slightly)
Appearance:	White to off-white powder
Storage:	Store at 2-8°C
MDL:	MFCD09261382
LogP:	-0.92890
pH:	3.0-6.0

GHS Hazard Statement:	H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Precautionary Statement:	P264, P280, P305+P351+P338, and P337+P313
Signal Word:	Warning

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PMID	Publication Date	Title	Journal
21120566	20110501	Skin pretreatment with lasers promotes the transdermal delivery of vitamin C derivatives	Lasers in medical science
21202347	20080416	3-O-Ethyl-l-ascorbic acid	Acta crystallographica. Section E, Structure reports online
8603484	19951201	Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)	Carcinogenesis

Complexity:	259
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	2
Defined Bond Stereocenter Count:	0
Exact Mass:	204.06338810
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	6
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	204.06338810
Rotatable Bond Count:	4
Topological Polar Surface Area:	96.2 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-1.5