T-1105 - CAS 55321-99-8

Catalog: BB029001
Product Name: T-1105
CAS: 55321-99-8
Synonyms: 3,4-Dihydro-3-oxo-2-pyrazinecarboxamide; 3-Hydroxypyrazinamide; 3-Hydroxy-2-pyrazinecarboxamide; NSC 163503; 3-Hydroxypyrazine-2-carboxamide; 3-Oxo-3,4-dihydropyrazine-2-carboxamide; 3-Hydroxypyrazine-2-carboxylic acid amide; Pyrazinecarboxamide, 3,4-dihydro-3-oxo-
T-1105
IUPAC Name:2-oxo-1H-pyrazine-3-carboxamide
Description:T-1105, a structural analogue of T-705, is a broad-spectrum viral polymerase inhibitor that inhibits RNA viral polymerase after conversion to a ribonucleoside triphosphate (RTP) metabolite. It shows antiviral activity against various RNA viruses, including Zika virus (ZIKV), influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV) and foot-and-mouth disease virus (FMDV). It can be formed by nicotinamide mononucleotide adenylyltransferase.
Molecular Weight:139.11
Molecular Formula:C5H5N3O2
Canonical SMILES:C1=CN=C(C(=O)N1)C(=O)N
InChI:InChI=1S/C5H5N3O2/c6-4(9)3-5(10)8-2-1-7-3/h1-2H,(H2,6,9)(H,8,10)
InChI Key:SZPBAPFUXAADQV-UHFFFAOYSA-N
Boiling Point:640.8±55.0°C at 760 mmHg
Melting Point:>182°C (dec.)
Purity:≥96%
Density:1.63±0.1 g/cm3 (Predicted)
Solubility:Soluble in DMSO (Slightly), Aqueous Base (Slightly)
Appearance:Pale Brown to Brown Solid
Storage:Store at 2-8°C under inert atmosphere
MDL:MFCD00233977
LogP:-0.01860

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