3-Hydroxyflavone - CAS 577-85-5
Catalog: |
BB029822 |
Product Name: |
3-Hydroxyflavone |
CAS: |
577-85-5 |
Synonyms: |
Flavonol; 3-Hydroxy-2-phenyl-4H-chromen-4-one |
IUPAC Name: | 3-hydroxy-2-phenylchromen-4-one |
Description: | 3-Hydroxyflavone is a natural compound which can be isolated from the fruits of blueberries, showing antioxidant activity. |
Molecular Weight: | 238.24 |
Molecular Formula: | C15H10O3 |
Canonical SMILES: | C1=CC=C(C=C1)C2=C(C(=O)C3=CC=CC=C3O2)O |
InChI: | InChI=1S/C15H10O3/c16-13-11-8-4-5-9-12(11)18-15(14(13)17)10-6-2-1-3-7-10/h1-9,17H |
InChI Key: | HVQAJTFOCKOKIN-UHFFFAOYSA-N |
Boiling Point: | 393.7 °C at 760 mmHg |
Melting Point: | 171 to 172 °C |
Purity: | 98% |
Density: | 1.367 g/cm3 |
Solubility: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
Appearance: | Powder |
Decomposition: | When heated to decomposition it emits acrid smoke and irritating vapors |
MDL: | MFCD00006832 |
LogP: | 3.16560 |
Vapor Pressure: | 2.75X10-9 mm Hg at 25 °C (est) |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-10889557-B1 | Method of producing an alkoxyflavone derivative | 20191226 |
WO-2021119826-A1 | Extracts enriched with polyphenolic compounds and related methods | 20191219 |
WO-2021125011-A1 | Polymer, composition for organic electroluminescent element, composition for forming hole transport layer or hole injection layer, organic electroluminescent element, organic el display device, and organic el illuminator | 20191216 |
WO-2021125067-A1 | Cosmetic process using microneedle sheet | 20191216 |
WO-2021126078-A1 | Formulation, composition or foodstuff additives for the modification of glycemic response methods of manufacturing and using the same | 20191216 |
PMID | Publication Date | Title | Journal |
33276066 | 20210101 | Pretreatment of IEC-6\xa0cells with quercetin and myricetin resists the indomethacin-induced barrier dysfunction via attenuating the calcium-mediated JNK/Src activation | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
31655123 | 20200201 | Human CYP1A1 inhibition by flavonoids | Toxicology in vitro : an international journal published in association with BIBRA |
31756459 | 20200201 | Heterotropic activation of flavonoids on cytochrome P450 3A4: A case example of alleviating dronedarone-induced cytotoxicity | Toxicology letters |
32537472 | 20200101 | Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice | Journal of immunology research |
31124249 | 20191001 | Glucosylation of the phytoalexin N-feruloyl tyramine modulates the levels of pathogen-responsive metabolites in Nicotiana benthamiana | The Plant journal : for cell and molecular biology |
Complexity: | 366 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 238.062994177 |
Formal Charge: | 0 |
Heavy Atom Count: | 18 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 238.062994177 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 46.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.4 |
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