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| IUPAC Name: | 3-hydroxy-6-(trifluoromethyl)pyridine-2-carboxamide |
| Description: | 3-Hydroxy-6-(trifluoromethyl)picolinamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. |
| Molecular Weight: | 206.03 |
| Molecular Formula: | C7H5F3N2O2 |
| Canonical SMILES: | C1=CC(=NC(=C1O)C(=O)N)C(F)(F)F |
| InChI: | InChI=1S/C7H5F3N2O2/c8-7(9,10)4-2-1-3(13)5(12-4)6(11)14/h1-2,13H,(H2,11,14) |
| InChI Key: | ZKQCJQRSXIGDBJ-UHFFFAOYSA-N |
| References: | Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014). |
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