3-Fluoro-6-iodopicolinamide - CAS 1806419-36-2
Catalog: |
BB064631 |
Product Name: |
3-Fluoro-6-iodopicolinamide |
CAS: |
1806419-36-2 |
Synonyms: |
3-Fluoro-6-iodopyridine-2-carboxamide |
IUPAC Name: | 3-fluoro-6-iodopyridine-2-carboxamide |
Description: | 3-Fluoro-6-iodopicolinamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. |
Molecular Weight: | 266.01 |
Molecular Formula: | C6H4FIN2O |
Canonical SMILES: | C1=CC(=NC(=C1F)C(=O)N)I |
InChI: | InChI=1S/C6H4FIN2O/c7-3-1-2-4(8)10-5(3)6(9)11/h1-2H,(H2,9,11) |
InChI Key: | DTSXBCHRGAHXMI-UHFFFAOYSA-N |
References: | Oestereich, L., et al. Antiviral Res., 105, 17 (2014); Baranovich, T., et al. J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014). |
Complexity: | 167 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 265.93524 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 265.93524 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 56Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
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