3-(Dimethylamino)-1-(1-naphthyl)-1-propanone - CAS 10320-49-7
Catalog: |
BB001051 |
Product Name: |
3-(Dimethylamino)-1-(1-naphthyl)-1-propanone |
CAS: |
10320-49-7 |
Synonyms: |
3-(dimethylamino)-1-(1-naphthalenyl)-1-propanone; 3-(dimethylamino)-1-naphthalen-1-ylpropan-1-one |
IUPAC Name: | 3-(dimethylamino)-1-naphthalen-1-ylpropan-1-one |
Description: | 3-(Dimethylamino)-1-(1-naphthyl)-1-propanone (CAS# 10320-49-7) is a compound related to TMC207 which is used in the treatment of drug-resistant tuberculosis, and was studied for its anti-tubercular activity. |
Molecular Weight: | 227.30 |
Molecular Formula: | C15H17NO |
Canonical SMILES: | CN(C)CCC(=O)C1=CC=CC2=CC=CC=C21 |
InChI: | InChI=1S/C15H17NO/c1-16(2)11-10-15(17)14-9-5-7-12-6-3-4-8-13(12)14/h3-9H,10-11H2,1-2H3 |
InChI Key: | CXDXSNWZXJVDMC-UHFFFAOYSA-N |
Boiling Point: | 368.7 °C at 760 mmHg |
Density: | 1.072 g/cm3 |
MDL: | MFCD09753763 |
LogP: | 2.97420 |
Publication Number | Title | Priority Date |
KR-102303635-B1 | PROCESS FOR PREPARING (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol AND PHARMACEUTICALLY ACCEPTABLE SALT | 20200701 |
US-2020345661-A1 | Small molecule cmklr1 antagonists in inflammatory disease | 20190502 |
WO-2020161743-A1 | Process for the preparation of bedaquiline fumarate | 20190208 |
TW-201725198-A | Preparation method of pyridine derivative compound, intermediate and crystal form thereof | 20160113 |
WO-2017121323-A1 | Preparation method for pyridine derivative compound, intermediate and crystal form thereof | 20160113 |
PMID | Publication Date | Title | Journal |
21587812 | 20100605 | (1R*,2R*)-1-(4-Chloro-phen-yl)-4-dimethyl-amino-1-(3-meth-oxy-2-naphth-yl)-2-(1-naphth-yl)butan-2-ol | Acta crystallographica. Section E, Structure reports online |
21580392 | 20100213 | (1R*,2R*)-1-(7-Bromo-3-methoxy-naphthalen-2-yl)-4-(dimethyl-amino)-2-(naphthalen-1-yl)-1-phenyl-butan-2-ol | Acta crystallographica. Section E, Structure reports online |
Complexity: | 262 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 227.131014166 |
Formal Charge: | 0 |
Heavy Atom Count: | 17 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 227.131014166 |
Rotatable Bond Count: | 4 |
Topological Polar Surface Area: | 20.3 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.8 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS