Description: | 3-Cyclobutoxy-4-(difluoromethoxy)benzoic Acid is an intermediate for the synthesis of O-Des(Cyclopropylmethyl) O-cyclobutyl Roflumilast (C982940), which is an intermediate used in the synthesis of Roflumilast (R639700). Roflumilast is a selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; used in treatment of chronic obstructive pulmonary disease. |
Molecular Weight: | 258.22 |
Molecular Formula: | C12H12F2O4 |
Solubility: | DMSO |
Appearance: | White Solid |
Storage: | Refrigerator |
References: | Hatzelmann, A., et al. J. Pharmacol. Exp. Ther., 297, 267 (2001); Schmidt, B.M.W., et al. J. Allergy Clin. Immunol., 108, 530 (2001); Timmer, W., et al. J. Clin. Pharmacol., 42, 297 (2002); Rabe, K.F., et al. Lancet, 366, 563 (2005). |
Customer Support
If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
Copyright © 2024 BOC Sciences. All rights reserved.
Our Products